GNC Holdings Inc. (General Nutrition Centers) is a Pittsburgh, Pennsylvania-based American company selling health and nutrition related products, including vitamins, supplements, minerals, herbs, sports nutrition, diet, and energy products. In 1935, David Shakarian opened a small health food store, Lackzoom, in downtown Pittsburgh. In 1990 the company considered relocating but a public/private effort retained GNC headquarters in Downtown Pittsburgh. GNC was taken private and sold to The Thomas Lee Company, a PE investment/management fund in the late 1980s. Thomas Lee ran GNC and took it public prior to selling the company to Royal Dutch Numico and Numico acquired GNC in 1999; it sold GNC to Apollo Management in 2003. Ontario Teachers' Pension Plan and Ares Management bought GNC in 2007. GNC went public in 2011. In 2018, Harbin Pharmaceutical Group Holding Co., a company controlled by the Chinese government, agreed to acquire an approximately 40% stake in GNC. In June 2019, the company announced they would be shuttering 900 mall locations in 2020 due to slumping sales. GNC stores typically stock a wide range of weight loss, bodybuilding, nutritional supplements, vitamins, natural remedies, and health and beauty products, in both its owned brands as well as third-party brands. In July 2019, it was announced that GNC plans to close up to 900 retail locations, primarily those located within shopping malls.

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